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Clinical Case in Oncology

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Effectiveness of biotherapy with somatostatin analogues in the treatment of a patient with carcinoid syndrome with neuroendocrine tumors of the pancreas

https://doi.org/10.62546/3034-1477-2024-2-1-37-43

Abstract

Neuroendocrine tumors are nowadays diagnosed quite often and it is important to know that they often lead to carcinoid syndrome due to the production of serotonin by the cells. Clinical manifestations of carcinoid syndrome (flushes, erythema of the skin of the face, neck, chest, development of diarrhea, etc.) significantly reduce the quality of life of patients. Personalized medicine implies a constant search for new means and ways to optimize the diagnosis of diseases and treatment of each patient. The subject of this article is a specific clinical case of carcinoid syndrome in pancreatic NET. The aim of the work is to analyze the effectiveness of biotherapy with somatostotin analogues in the treatment of carcinoid syndrome in pancreatic NET on the example from clinical practice. When discussing the problems of treatment of a patient with carcinoid syndrome in pancreatic NEТ the results of laboratory tests, data of various methods of diagnostics and treatment are used. To confirm the effectiveness of biotherapy with somatostotin analogs, visual material (photos of the patient in dynamics) is offered.

About the Authors

E. V. Markarova
Moscow Research Clinical Institute named after M. F. Vladimirsky (MONIKI)
Russian Federation

Markarova Ekaterina Vasilievna — Candidate of Medical Sciences, Associate Professor of the Department of Oncology and Thoracic Surgery of the State Educational Institution of Higher Education



L. M. Kogonia
Moscow Research Clinical Institute named after M. F. Vladimirsky (MONIKI)
Russian Federation

Kogonia Lali Mikhailovna  — Doctor of Medical Sciences, Professor, Professor of the Department of Oncology and
Thoracic Surgery, Federal Higher Educational Institution



E. V. Bondarenko
Moscow Research Clinical Institute named after M. F. Vladimirsky (MONIKI); Biobanking Center of the State Research Center of the Russian Federation of the National Medical Research Center of Endocrinology
Russian Federation

Bondarenko Ekaterina Vladimirovna  — Ph.D. Head of the Biobanking Center of the State Research Center ; senior researcher at the Department of Morphological Diagnostics of the Oncology Department



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Review

For citations:


Markarova E.V., Kogonia L.M., Bondarenko E.V. Effectiveness of biotherapy with somatostatin analogues in the treatment of a patient with carcinoid syndrome with neuroendocrine tumors of the pancreas. Clinical Case in Oncology. 2024;2(1):37-43. (In Russ.) https://doi.org/10.62546/3034-1477-2024-2-1-37-43

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