Lymphoproliferative disease: could they be localized in the pancreas?
https://doi.org/10.62546/3034-1477-2023-1-1-56-62
Abstract
Primary involvement of the pancreas in non-Hodgkin’s lymphoma is very rare. The symptoms of the tumor are nonspecific, and the results of instrumental diagnostics are often similar to pancreatic adenocarcinoma. Considering the fundamental differences in approaches to treatment and prognosis of these diseases, making an accurate diagnosis is only possible through morphological examination of tumor tissue samples. The difficulty of collecting a sufficient number of tissue samples, especially for immunohistochemical analysis, and the need for repeated tumor biopsies, in some cases lead to unnecessary surgical interventions.
About the Author
M. S. DinikinRussian Federation
Dinikin Mikhail Sergeyevich — surgeon-oncologist abdominal oncology department No. 4
198255, Saint Petersburg, Veteranov Ave, 56
References
1. Armitage J. et al. Lymphomas. W.B. Saunders Company, 1988. 1st ed. Р. 439–449.
2. Sutcliffe S., Gospodarowicz M. Localized extranodal lymphomas // Haematological Oncology. Medical Reviews. Cambridge, 1992. Р. 189–222.
3. Behrns K.E., Sarr M.G., Strickler J.G. Pancreatic lymphoma: is it a surgical disease? // Pancreas. 1994. Vol. 9, No. 5. Р. 662–667.
4. Gress F., Gottlieb K., Sherman S. et al. Endoscopic ultrasonography-guided fine-needle aspiration biopsy of suspected pancreatic cancer // Ann. Intern. Med. 2001. Vol. 134. Р. 459–464.
5. Nayer H., Weir E.G., Sheth S., Ali S.Z. Primary pancreatic lymphomas; a cytopathologic analysis of a rare malignancy // Cancer. 2004. Vol. 102, No. 5. Р. 315–321.
6. Huo Y.J., Zhang M.C., Shi Q., Qin W., Shi Z.Y., Wang L., Cheng S., Xu P.P., Zhao W.L. Clinical characteristics and prognosis of primary and secondary diffuse large B-cell lymphoma of the pancreas // Zhonghua Xue Ye Xue Za Zhi. 2023. Vol. 44, No. 1. Р. 55–61. Chinese. doi: 10.3760/cma.j.issn.0253–2727.2023.01.010.
7. Mishra M.V., Keith S.W., Shen X. et al. Primary pancreatic lymphoma: a population-based analysis using the SEER program // Am.J.Clin. Oncol. 2013. Vol. 36, No. 1. Р. 38–43. doi: 10.1097/COC.0b013e3182354bbb.
8. Li Z., Zhang S., Vasdani N. et al. Clues for diagnosing primary pancreatic lymphoma // Case Rep. Gastroenterol. 2012. Vol. 6. Р. 438–445.
9. Saif M.W. Primary pancreatic lymphomas // JOP. 2006. Vol. 7. Р. 262–273.
10. Dawson I.M., Cornes J.S., Morson B.C. Primary malignant lymphoid tumours of the intestinal tract. Report of 37 cases with a study of factors influencing prognosis // Br.J.Surg. 1961. Vol. 49. Р. 80–89.
11. Merkle E.M…, Bender G.N…, Brambs H.J. Imaging findings in pancreatic lymphoma: differential aspects // AJR.Am.J. Roentgenol. 2000. Vol. 174. Р. 671–675.
12. Lamrani F.Z., Amri F., Koulali H. et al. Primary pancreatic lymphoma: Report of 4 cases with literature review // Radiol. Case Rep. 2023 Oct 21. Vol. 19, No. 1. Р. 70–77. doi: 10.1016/j.radcr.2023.09.067.
13. Alzerwi N.A. Primary pancreatic lymphoma masquerading as carcinoma // Case Rep. Oncol. Med. 2020. Vol. 2020. Р. 5160545.
14. Dunphy L., Abbas S.H., Al Shoek I., Al-Salti W. Primary pancreatic lymphoma: a rare clinical entity // BMJ Case Rep. 2020. Vol. 13. Р. 0.
15. Koniaris L.G., Lillemoe K.D., Yeo C.J. et al. Is there a role for surgical resection in the treatment of early-stage pancreatic lymphoma? // J.Am.Coll Surg. 2000. Vol. 190. Р. 319–330.
16. Muller M.F., Meyenberger C., Bertschinger P. et al. Pancreatic tumors: evaluation with endoscopic US, CT, and MR imaging // Radiology. 1994. Vol. 190. Р. 745–751.
17. Ullah A., Lee K.T., Malham K. et al. Pancreatic Diffuse Large B-cell Lymphoma in the US Population // Cureus. 2023 Jun 2. Vol. 15, No. 6. e39862. doi: 10.7759/cureus.39862.
18. Huo Y.J., Zhang M.C., Shi Q. et al. Clinical characteristics and prognosis of primary and secondary diffuse large Bcell lymphoma of the pancreas // Zhonghua Xue Ye Xue Za Zhi. 2023. Jan 14. Vol. 44, No. 1. Р. 55–61. doi: 10.3760/cma.j.issn.0253-2727.2023.01.010.
19. Dunphy L., Abbas S.H., Al Shoek I. et al. Primary Pancreatic lymphoma: a rare clinical entity[J] // BMJ Case Rep. 2020. Vol. 13, No. 1. e231292. doi: 10.1136/bcr-2019-231292.
20. Клинические рекомендации МЗ РФ «Рак поджелудочной железы» 2021. https://cr.minzdrav.gov.ru/recomend/355.
21. Zhu N-X., Wang X-Y., Tong T. et al. Primary pancreatic lymphoma diagnosed by endoscopic ultrasound-guided fine needle biopsy // Hepatobiliary Pancreat Dis Int. 2022. Vol. 21, No. 1. Р. 99–102. doi: 10.1016/j.hbpd.2021.05.001.
22. Bronstein Y.L., Loyer E.M., Kaur H. et al. Detection of small pancreatic tumors with multiphasic helical CT // AJR Am.J.Roentgenol. 2004. Vol. 182. Р. 619–623.
23. Eloubeidi M.A., Jhala D., Chhieng D.C. et al. Yield of endoscopic ultrasound-guided fine-needle aspiration biopsy in patients with suspected pancreatic carcinoma // Cancer. 2003. Vol. 99. Р. 285–292.
24. Anand D., Lall C., Bhosale P. et al. Current update on primary pancreatic lymphoma // Abdom. Radiol. (NY). 2016. Vol. 41, No. 2. Р. 347–355. doi: 10.1007/s00261-015-0620-8.
25. Berger A.C., Garcia Jr.M., Hoffman J.P. et al. Postresection CA 19–9 predicts overall survival in patients with pancreatic cancer treated with adjuvant chemoradiation: a prospective validation by RTOG 9704 // JCO. 2008. Vol. 26, No. 36. Р. 918–5922. doi: 10.1200/JCO.2008.18.6288.
26. Lin H. Primary pancreatic lymphoma: report of six cases // WJG. 2006. Vol. 12, No. 31. Р. 5064. doi: 10.3748/wjg.v12.i31.5064.
27. Du X., Zhao Y., Zhang T., Liao Q., Dai M., Liu Z. et al. Primary pancreatic lymphoma: a clinical quandary of diagnosis and treatment // Pancreas. 2011. Vol. 40, No. 1. Р. 30–36. doi: 10.1097/MPA.0b013e3181e6e3e5.
28. Yu L., Chen Y., Xing L. Primary pancreatic lymphoma: two case reports and a literature review // OTT. 201. Vol. 10. Р. 1687–1694. doi: 10.2147/OTT.S121521.
Review
For citations:
Dinikin M.S. Lymphoproliferative disease: could they be localized in the pancreas? Clinical Case in Oncology. 2023;1(1):56-62. (In Russ.) https://doi.org/10.62546/3034-1477-2023-1-1-56-62