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Clinical Case in Oncology

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Advanced small cell lung cancer with first diagnosed HIV infection

https://doi.org/10.62546/3034-1477-2025-3-2-31-38

Abstract

Nowadays, small cell lung cancer and HIV infection can be under controlled diseases, and specialists have approved clinical guidelines for treating these conditions. However, given the life expectancy of patients with HIV infection on antiretroviral therapy and patients with small cell lung cancer on polychemotherapy, doctors often encounter cases of these conditions combined in practice. This article presents a clinical case of detection of metastatic nonsmall cell lung cancer and HIV infection at the same time. The main purpose of this article is to demonstrate the modern possibilities of treating lung cancer in persons with HIV using multidisciplinary approach.

About the Authors

P. S. Gavrilov
Pavlov First St. Petersburg State Medical University; City Clinical Oncological Dispensary
Russian Federation

Pavel S. Gavrilov

Leo Tolstoy St., 6–8, St. Petersburg, 197022

56 Veteranov Ave., St. Petersburg, 198255



D. A. Polezhaev
Pavlov First St. Petersburg State Medical University; City Clinical Oncological Dispensary
Russian Federation

Dmitry A. Polezhaev

Leo Tolstoy St., 6–8, St. Petersburg, 197022

56 Veteranov Ave., St. Petersburg, 198255



N. A. Karaseva
City Clinical Oncological Dispensary
Russian Federation

Nina A. Karaseva

56 Veteranov Ave., St. Petersburg, 198255



S. I. Kutukova
Pavlov First St. Petersburg State Medical University; City Clinical Oncological Dispensary
Russian Federation

Svetlana I. Kutukova

Leo Tolstoy St., 6–8, St. Petersburg, 197022

56 Veteranov Ave., St. Petersburg, 198255



R. Ya. Gunyat
City Clinical Oncological Dispensary; S. M. Kirov Medical Military Academy
Russian Federation

Ruslan Ya. Gunyat

56 Veteranov Ave., St. Petersburg, 198255

6, Akademika Lebedeva street, St. Petersburg, 194044



G. M. Manikhas
Pavlov First St. Petersburg State Medical University; City Clinical Oncological Dispensary
Russian Federation

Georgy M. Manikhas

Leo Tolstoy St., 6–8, St. Petersburg, 197022

56 Veteranov Ave., St. Petersburg, 198255



References

1. Hoffman C., Rockstroh J.K. HIV [Internet]. Germany, 2020. Available from: https://www.hivbuch.de/wp-content/uploads/2020/12/HIV2015-16_GB.pdf.

2. Centers for Disease Control and Prevention // HIV Surveillance Report. 2016. Vol. 28. http://www.cdc.gov/hiv/library/reports/hiv-surveillance.html. 2017.

3. Orenstein J.M. Ultrastructure of HIV/AIDS // Ultrastruct. Pathol. 2002. Vol. 26. Р. 245–250.

4. Nekrasova A.V. Clinical and morphological characteristics, treatment results and prognosis of malignant neoplasms in HIV infection: diss. ... candidate of medical sciences. Obninsk, 2021. Access mode: https://kgma.info/files/dissovet/diss_nav_22_12_2021.pdf (In Russ.).

5. Worm S.W., Bower M., Reiss P. et al. Non-AIDS defining cancers in the D:A:D study-time trends and predictors of survival: a cohort study // BMC Infect. Dis. 2013. Vol. 13. Р. 471.

6. Tanaka T., Oshima K., Kawano K. et al. Nationwide Longitudinal Annual Survey of HIV/AIDS Referral Hospitals in Japan From 1999 to 2021: Trend in Non-AIDS-defining Cancers Among Individuals Infected With HIV-1 // J. Acquir. Immune Defic. Syndr. 2024. May 1; Vol. 96, No. 1. Р. 1–10.

7. Marcus J.L., Chao C., Leyden W.A. et al. Survival among HIV-infected and HIV-uninfected individuals with common non-AIDS-defining cancers // Cancer Epidemiol Biomarkers Prev. 2015. Vol. 24, No. 8. Р. 1167–1173.

8. HIV infection in the Russian Federation as of December 31, 2022. Data were obtained in 1987–2023 from territorial centers for the prevention and control of AIDS (or other authorized organizations) and territorial Directorates of the Federal Service for Surveillance on Consumer Rights Protection and Human Wellbeing. Specialized Research Department for the Prevention and Control of AIDS, Central Research Institute of Epidemiology of Rospotrebnadzor (In Russ.)] URL: http://www.hivrussia.info/wpcontent/uploads/2023/09/Spravka-VICH-v-Rossii-na-31.12.2022.pdf.

9. Suneja G., Boyer M., Yehia B.R. et al. Cancer treatment in patients with HIV infection and non-AIDS-defining cancers: a survey of US oncologists // J. Oncol. Pract. 2015. Vol. 11. Р. 380–387.

10. Hleyhel M., Bouvier A.M. et al. Risk of non-AIDS-defining cancers among HIV-1 infected individuals in France between 1997 and 2009: results from a French cohort // AIDS. 2014. Vol. 28. Р. 2109–2118.

11. Makinson A., Tenon J.C., Eymard-Duvernay S. et al. Human immunodeficiency virus infection and non-small cell lung cancer: survival and toxicity of antineoplastic chemotherapy in a cohort study // J. Thorac. Oncol. 2011. Vol. 6. Р. 1022–1029.


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For citations:


Gavrilov P.S., Polezhaev D.A., Karaseva N.A., Kutukova S.I., Gunyat R.Ya., Manikhas G.M. Advanced small cell lung cancer with first diagnosed HIV infection. Clinical Case in Oncology. 2025;3(2):31-38. (In Russ.) https://doi.org/10.62546/3034-1477-2025-3-2-31-38

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ISSN 3034-1477 (Print)